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PMCID: PMC6271067.

It may help if pigmentation-related, but results vary

Peripheral neuropathy, subacute combined degeneration of the spinal cord, or cognitive impairment indicate more advanced deficiency and generally require intensive treatment over extended periods

The most common myelin disorder of the CNS is multiple sclerosis (MS), characterized by motor, sensory and cognitive impairments resulting from demyelinating lesions, considered to be initiated by transgression of immune constituents across blood-brain and cerebrospinal fluid (CSF) barriers

To calculate the relative expression ratios of genes of interest within each cell type and species, we used the original gene counts from these RNA-sequencing data sets